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. Author manuscript; available in PMC: 2007 Nov 10.
Published in final edited form as: Virology. 2006 Dec 22;361(2):426–434. doi: 10.1016/j.virol.2006.10.047

Figure 3.

Figure 3

Central section through an averaged tomographic reconstruction of A-capsids. 150 individual tomograms were mutually aligned, with their portal/connector vertex (p/c) at the top, and averaged. Noise was further reduced by 5-fold averaging about the symmetry axis running vertically in the center of this plane. The 12-fold rotational symmetry of the portal is amplified to 60-fold symmetry by this operation: at the current resolution (5 nm), this is tantamount to cylindrical averaging about the local symmetry axis. Nevertheless, the average distribution of density along this axis and perpendicular to it, at this vertex site, are correctly conveyed. In these respects, this vertex site differs markedly from the vertices (P) occupied by pentamers of UL19. Bar = 20 nm.