Multiple nucleotide sequence alignment of the 3′ end of synC and downstream sequence in serogroups B (strain NMB), C (strain FAM18), W-135 (strain GA1002), and Y (strain GA0929) N. meningitidis [Pretty multiple sequence comparison program of the Genetics Computer Group sequence analysis package version 7.3.1 UNIX (33)]. Consensus nucleotide matches (three or more identical) at each position are indicated in uppercase type, while differences from consensus are indicated by lowercase type. Dots indicate gaps introduced by the analysis program to facilitate alignment. The synC termination codon (TAA) and the synD/E/F start codons (ATG) are shown in boldface type. The location of an IS1301 element located downstream of the synC gene in the otherwise identical sequence of a second serogroup W-135 strain, 6083, is shown in the GA1002 sequence by a ^. The complete sequence of synE derived from serogroup C strain FAM18 is available through the GenBank data base under accession no. U75650U75650.