Table 2.

Clinical, Transcranial Doppler (internal carotid (ICA)/middle cerebral artery (MCA), haematology, magnetic resonance angiography (MRA) and sleep study data from 19 patients from the East London cohort who had a central nervous system event during a prospective study (Kirkham et al., 2001)

										Overnight oxyhaemoglobin saturation
Patient	Sex	Haemoglo binopathy	Age	Cerebro-vascular disease on MRA	Initial ICA/MCA Velocity	Maximum ICA/MCA Velocity during follow-up	Hb	Mean reticulocytes	Ts & As	Mean	Min	% <80%	% <90%	Sleep study result
1	M	SS	4.98	N	126	144	7.8	11.9	N	93.34	71	.96	11.6	Normal
2	M	SS	7.04	N	100	138	10.7	5.8	N	97.89	67	.28	2.18	Normal
3	M	SS	6.74	N	108	139	9.1	9.5	Y	98.23	86	.00	.35	Normal
4	F	SS	3.46	N	140	152	11.4	3.2	N	98.64	82	.00	1.03	Normal
5	M	SC	6.53	N	137	137	13.3	2.7	N	95.37	85	.00	1.29	Normal
6	M	SB	8.88	Y	137	137	12.6	13.5	N	95.77	85	.00	1.68	Normal
7	F	SS	9.63	Y	258	258	7.3	10.6	N	92.96	81	.00	13.5	Dips
8	F	SS	2.82	Y	143	144	10.9	11.5	N	97.70	90	.00	.13	Normal
9	M	SS	5.47	Y	116	141	6.9	17.1	N	90.21	76	.92	42.5	Normal
10	F	SS	9.43	Y	228	267	6.5	8.6	N	95.22	85	.00	1.32	Dips
11	F	SS	9.63	Y	134	134	8.1	11.6	N	95.68	41	.00	4.09	Normal
12	M	SS	4.74	Y	167	167	7.6	17.1	Y	90.58	75	.00	38.1	Dips
13	M	SS	4.69	Y	198	198	8.1	12.3	Y	87.00	76	.50	50.0	Mean <92%
14	M	SS	13.29	Y	131	131	8.1	18.4	N	87.26	77	1.05	97.5	Dips
15	F	SS	10.23	Y	72	88	6.8	–	N	91.93	81	.00	6.51	Mean <92%
16	F	SS	10.16	Y	109	124	11.1	16.9	Y	94.70	75	.29	3.37	Normal
17	F	SS	2.74	Y	125	125	8.5	8.5	N	97.05	84	.00	2.60	Normal
18	M	SS	11.01	Y	98	98	6.5	6.2	Y	85.00	75			Dips
19	M	SS	4.33	Y	134	134	10.2	16.3	N	92.41	89	.00	.00	Normal

MRA Magnetic resonance angiography, ICA internal carotid artery, MCA middle cerebral artery, Hb Haemoglobin, Dips desaturations, Ts & As Adenotonsillectomy.