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. 2007 Aug;97(8):1457–1463. doi: 10.2105/AJPH.2006.094086

TABLE 2—

Associations Between Exposure to Workplace Secondhand Smoke and Any Detectable Level of Total NNAL, Nicotine, and Cotinine in the Postworkshift Urine of Nonsmoking Food Service Workers; Oregon, November 2004–August 2005

No.a % Having Any Detectable Levelb Adjusted OR (95% CI)c
Total NNAL
    Protected workers (reference) 31 45.2 1.00
    Exposed Workers 50 76.0 5.66 (1.67, 19.14)*
Total nicotine
    Protected workers (reference) 32 9.4 1.00
    Exposed workers 52 90.4 109.01 (20.42, 581.77)**
Total cotinine
    Protected workers (reference) 32 18.8 1.00
    Exposed workers 52 92.3 95.21 (15.97, 567.61)**

Notes. NNAL = 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol; OR = odds ratio; CI = confidence interval.

aTotal NNAL (pmol/mL) could not be determined in 3 participants’ urine samples.

bDetection limits: cotinine, 2 ng/mL; nicotine, 2 ng/mL; NNAL, 0.007–0.01 pmol/mL. In nonsmokers, the half-life for nicotine is 2 hours,56 for cotinine is 16.9 hours,56 and for NNAL is unknown. In smokers, the half-life for nicotine is 2.6 hours,56 for cotinine is 17.5 hours,56 and for NNAL is 3–4 days for the distribution phase and 40–45 days for the elimination phase.51

cOdds ratios were based on logistic regression and adjusted for participant age, gender, and minutes exposed to secondhand smoke outside the workplace in the past week.

* P < .01; **P < .001.