Table 1.

Binding affinities were calculated by frontal affinity chromatography using the immobilized P2Y1 receptor columns, where the affinities are presented as Kd values ± the Standard Error of the Mean. The chromatographic results are compared to binding affinities reported in literature [6,10].

	2-MeSADP (nM)	MRS-2179 (nM)	ATP (μM)
P2Y1-IAM	186.4 ± 85.7	199.0 ± 4.5	1.38 ± 0.94
Literature	50 ± 10[10]	117 ± 9 [10] 109 ± 7 [6]	14 ± 6 [10]