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Time course of tumor development
| Time (d)* | Colonization | Invasion | Tissue damage | Metastasis |
|---|---|---|---|---|
| <10 | – | – | – | – |
| 10 | + | +/ – | – | – |
| 15 | + | + | + | – |
| >21 | + | + | + | + |
| Dose dependence of intravitreous inoculation for tumor development | ||||
|
| ||||
| Cell number† | Colonization | Invasion | Tissue damage | Metastasis |
|
| ||||
| <6,000 | – | – | – | – |
| 6,000-20,000 | + | +/ – | +/ – | – |
| >20,000 | + | + | + | + |
NOTE: Data are collection of six independent experiments.
Time after tumor injection.
Total cell numbers per eye per intravitreous injection.
