Histograms showing the relationship between AFP-L3% and tumor characteristics: 3A, tumor size; 3B, tumor stage; 3C, vascular invasion; and 3D, histologic grade. The means were calculated without taking into consideration AFP-L3 values which were not detected (ND), not reported (NR), not measurable because the total AFP was undetected (U), or not measurable because the total AFP was >300,000 ng/ml (H). There is little effect of L3% for tumor size, tumor grade, and vascular involvement. There is a possible trend for TNM, but the numbers are small.