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. Author manuscript; available in PMC: 2008 Mar 1.
Published in final edited form as: Clin Gastroenterol Hepatol. 2007 Mar;5(3):394–267. doi: 10.1016/j.cgh.2006.12.005

Table 3.

Survival characteristics of hepatocellular carcinoma patients by AFP-L3%

Variable AFP-L3 (%)

<10 (n=85) =10(n=80) Total
Total AFP 10-200 (ng/ml)
 Number of Subjects 15 37 52
 Observed Deaths 6 17 23
 Expected Deaths 10.44 21.03 31.48
 O/E ratio (95% CI) 0.57 (0.21-1.25) 0.81 (0.47-1.29) 0.73 (0.46-1.10)
Total AFP >200 (ng/ml)
 Number of Subjects 8 43 51
 Observed Deaths 6 36 42
 Expected Deaths 3.01 17.10 20.11
 O/E ratio (95% CI) 1.99 (0.73-4.33) 2.11 (1.47-2.91) 2.09 (1.50-2.82)
All HCC with AFP =10 (ng/ml)
 Number of Subjects 23 80 103
 Observed Deaths 12 53 65
 Expected Deaths 13.46 38.13 51.59
 O/E ratio (95% CI) 0.89 (0.46-1.56) 1.39 (1.04-1.82) 2.28 (0.97-1.61)

Expected Deaths Adj. AFP 13.74 51.26
 O/E ratio (95% CI) 0.9 (0.45-1.53) 1 (0.77-1.35)

* Expected deaths estimated from the number of deaths during follow-up

The model chi squares for the analyses stratified by total AFP were not significant, thus the analyses performed were for the combined AFP groups

O/E observed/expected ratio.