TABLE 1.

DNA repair genes included in this study

S. pombe gene	S. cerevisiae closest homolog	Function in S. pombe
lig4+	DNL4	ATP-dependent DNA ligase involved in NHEJ (Baumann and Cech 2000)
pku70+	YKU70	DNA-binding protein involved in DNA repair and telomere maintenance (Baumann and Cech 2000)
exo1+	EXO1	5′ → 3′ exonuclease (XP-G family) involved in several DNA repair pathways such as MMR (Rudolph et al. 1998) and possibly HR (Tomita et al. 2003)
rad2+	RAD27	ssDNA endonuclease (XP-G family) homologous to FEN-1; involved in mismatched DNA repair (Kunz and Fleck 2001) and telomere maintenance (Dahlen et al. 2003)
rad13+	RAD2	ssDNA endonuclease (XP-G family) involved in NER (Kunz and Fleck 2001)
spac12g12.16c+	RAD27	Member of the XP-G family of nucleases with unknown function
rad22+	RAD52	Annealing of complementary single-stranded DNA; required for HR (Hegde et al. 1996; van den Bosch et al. 2001, 2002)
rhp51+	RAD51	AAA ATPase with strand displacement activity involved in HR and telomere maintenance (Kibe et al. 2003)
rqh1+	SGS1	DEAD/DEAH box DNA helicase (RecQ family) involved in HR-dependent DSB repair (Hegde et al. 1996)
msh2+	MSH2	DNA mismatch repair protein (MutS homolog) required for MMR (Rudolph et al. 1998)
pms1+	PMS1	DNA mismatch repair protein (MutL homolog) required for MMR (Rudolph et al. 1998)
swi10+	RAD10	ssDNA repair endonuclease (ERCC1 family); forms a complex with Rad16 and is involved in NER (Carr et al. 1994; Rodel et al. 1997)
rad16+	RAD1	ssDNA repair endonuclease (XP-F family); forms a complex with Swi10 and is involved in NER (Carr et al. 1994; Rodel et al. 1997)
pol4+	POL4	PolX DNA polymerase with gap-filling activity; combines properties of mammalian DNA polymerase β, μ, and λ; possibly involved in BER and NHEJ (Gonzalez-Barrera et al. 2005)
rad50+	RAD50	AAA ATPase involved in sister-chromatid recombination (Hartsuiker et al. 2001) and intermolecular NHEJ (Decottignies 2005)