Table 2.
Lymphocyte subpopulations in members of family 86
| Percent of lymphoid cells (absolute numbers/mm3) | ||||||
| Pt | Sib1 | Sib2 | Mother | Father | Controls** | |
| Total T Cells | ||||||
| CD3 | 64.7(2750) | 78.6(1336) | 80.3(1767) | 71.1(1138) | 65.1(1172) | (832–2028) |
| CD5 | 62.8(2669) | 79.3(1348) | 81.8(1800) | 72.4(1158) | 68.8(1238) | (828–1994) |
| CD3/ab | 51.8(2202) | 47.1(801) | 75.4(1659) | 69.9(1118) | 64(1152) | (620–2010) |
| CD3/gd | 12(510) | 5.3(90) | 5.3(117) | 0.9(14) | 0.9 (16) | (9–166) |
| T Cell Subsets | ||||||
| CD4 | 36.1(1534) | 43.3(736) | 52(1144) | 41.9(670) | 40.6(731) | (480–1339) |
| CD8 | 26.7(1135) | 31.8(541) | 31.6(695) | 33.5(536) | 29.6(533) | (351–911) |
| CD3+CD4-CD8- | 9.7(412) | 4.6(78) | 4.9(108) | 1.1(18) | 1.3(23) | (9–122) |
| DNT/ab* | 1.1(47) | 0.8(14) | 1.1(24) | 0.5(8) | 0.5(9) | (2–18) |
| DNT/gd | 7.9(336) | 3.9(66) | 3.4(75) | 0.6(10) | 0.7(13) | (5–59) |
| T Cell Activation | ||||||
| CD4+/HLA-DR+ | 14.2(604) | 1.6(27) | 2.3(51) | 2.8(45) | 2.7(49) | (< = 95) |
| CD4+/CD25+ | 5.2(221) | 16.1(274) | 11(242) | 19.7(315) | 22.1(398) | |
| Total B cells | ||||||
| CD20 | 18.9(803) | 8.8(150) | 8.1(178) | 5.9(94) | 19.6(353) | (88–330) |
*DNT: Double-negative CD4- CD8- T cells, either TCRαβ+ or TCRγδ+
** 95% confidence intervals for adult normals.