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. 2007 Aug 8;2(8):e702. doi: 10.1371/journal.pone.0000702

Figure 3. Mammalian alignment of the inverted repeat element.

Figure 3

Sequences comprising the inverted repeat elements from 10 mammalian species were aligned using the multi-Lagan tool. To demonstrate their sequence homology, distal IRE and proximal IRE are shown in a forward and reverse orientation, respectively. Both IREs contain multiple conserved sequence motifs, including palindromic (PI-PIII) and direct (DRI) repeat sequences (shaded in grey), which likely function as transcription factor binding modules. Putative homeodomain transcription factor binding motifs are outlined in red.