Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Disruption of the MAP2-promoted microtubules by AD P-tau. The assembly of microtubules was determined turbidimetrically as described. The arrow indicates the time of addition of the AD P-tau (2 mg/ml final concentration) or the same volume of buffer to MAP2-preassembled microtubules. Samples of the reaction mixture were examined by negatively stained electron microscopy. Only an occasional microtubule was seen after 20 min of AD P-tau addition (not shown).
