Table 1.

Effect of normal tau on the binding of MAP1 and MAP2 to AD P-tau

Addition of	% bound protein
	MAP1, 70 μg	MAP2, 70 μg	Tau, 70 μg
Normal tau (8 μg)	12.3 ± 3.2	18.0 ± 3.6	14.3 ± 3.5
AD P-tau (8 μg)	24.0 ± 3.6	30.7 ± 2.4	45.7 ± 2.1
Normal tau (50 μg) plus AD P-tau (8 μg)	14.3 ± 3.5	19.7 ± 3.0	42.0 ± 2.7

The binding and the quantitation of the bound proteins were carried out in solution as described. Results represents the mean ± SD of six values. Addition of normal tau abolished the binding of MAP1 and MAP2 to AD P-tau.