TABLE 2.
MICs for antimicrobial agents tested against 110 toxigenic clinical C. difficile isolates
| Antimicrobial agent | MIC (μg/ml)
|
|||
|---|---|---|---|---|
| Range | MIC50 | MIC90 | Geometric mean | |
| Rifaximin | 0.0038->16 | 0.0075 | 0.015 | 0.009 |
| Rifalazil | 0.0019->16 | 0.0075 | 0.03 | 0.0067 |
| Tizoxanide | 0.015-0.5 | 0.06 | 0.125 | 0.0652 |
| Nitazoxanide | 0.03-0.5 | 0.06 | 0.125 | 0.076 |
| OPT-80 | 0.015-0.25 | 0.125 | 0.125 | 0.081 |
| Tigecycline | 0.06-1.0 | 0.125 | 0.25 | 0.142 |
| Metronidazole | 0.025-0.5 | 0.125 | 0.25 | 0.149 |
| Tinidazole | 0.03-1.0 | 0.125 | 0.25 | 0.165 |
| Ramoplanin | 0.06-0.5 | 0.25 | 0.5 | 0.291 |
| Vancomycin | 0.06-4.0 | 1.0 | 1.0 | 0.801 |
| Doripenem | 0.5-4.0 | 1.0 | 2.0 | 1.19 |
| Meropenem | 1.0-4.0 | 2.0 | 2.0 | 1.87 |
| Gatifloxacin | 0.5-64 | 1.0 | 16 | 1.752 |
| Moxifloxacin | 0.5-32 | 1.0 | 16 | 1.90 |
| Levofloxacin | 2.0-64 | 4.0 | 32 | 5.801 |