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. 2007 May 21;51(8):2716–2719. doi: 10.1128/AAC.01623-06

TABLE 2.

MICs for antimicrobial agents tested against 110 toxigenic clinical C. difficile isolates

Antimicrobial agent	MIC (μg/ml)
Antimicrobial agent	Range	MIC₅₀	MIC₉₀	Geometric mean
Rifaximin	0.0038->16	0.0075	0.015	0.009
Rifalazil	0.0019->16	0.0075	0.03	0.0067
Tizoxanide	0.015-0.5	0.06	0.125	0.0652
Nitazoxanide	0.03-0.5	0.06	0.125	0.076
OPT-80	0.015-0.25	0.125	0.125	0.081
Tigecycline	0.06-1.0	0.125	0.25	0.142
Metronidazole	0.025-0.5	0.125	0.25	0.149
Tinidazole	0.03-1.0	0.125	0.25	0.165
Ramoplanin	0.06-0.5	0.25	0.5	0.291
Vancomycin	0.06-4.0	1.0	1.0	0.801
Doripenem	0.5-4.0	1.0	2.0	1.19
Meropenem	1.0-4.0	2.0	2.0	1.87
Gatifloxacin	0.5-64	1.0	16	1.752
Moxifloxacin	0.5-32	1.0	16	1.90
Levofloxacin	2.0-64	4.0	32	5.801