Table 1.
Peptide | NK-3 receptor
|
NK-3 receptor homolog
|
||
---|---|---|---|---|
[3H]senktide | [125I-MePhe7]NKB | [3H]senktide | [125I-MePhe7]NKB | |
SP | 2960 ± 60* | >10,000 | 4450 ± 390 | >10,000 |
NKA | 2390 ± 230 | 7250 ± 2300 | 9150 ± 2440 | >10,000 |
NKB | 13 ± 1* | 17 ± 4** | >10,000 | 126 ± 27 |
Senktide | 84 ± 5 | 312 ± 81 | 127 ± 26 | 211 ± 14 |
[MePhe7]NKB | 5.3 ± 0.5* | 12 ± 2* | 12 ± 1 | 45 ± 6 |
The data reported for [3H]senktide competition is derived from the data shown in Fig. 2.
Significantly different at P < 0.05 compared with that obtained at the NK-3 receptor homolog, using unpaired t test on logarithmically transformed data.