Table 2.

Summary of the EC₅₀ values for stimulation of inositol phospholipid turnover and arachidonic acid release in CHO cell lines expressing the human NK-3 receptor and human NK-3 receptor homolog

Peptide	NK-3 receptor		NK-3 receptor homolog
	Inositol phosphate	Arachidonic acid	Inositol phosphate	Arachidonic acid
SP	128  ± 38	153  ± 43	214 ± 143	552  ± 244
NKA	77  ± 11	120  ± 37	54 ± 16	237  ± 67
NKB	1.1  ± 0.5	9.3  ± 0.1	0.75 ± 0.02	4.2  ± 3.0
Senktide	5.1  ± 0.7	7.1  ± 2.4	2.3 ± 2.1	2.8  ± 1.3
[MePhe7]NKB	0.5  ± 0.1	0.6  ± 0.2	7.1 ± 6.4	0.6  ± 0.5

The data reported in this table summarizes experiments presented in Figs. 3 and 4. Statistical analysis by unpaired t tests of EC₅₀ values for each second messenger response at the two receptors did not yield any significant differences at the P < 0.05 level.