TABLE 5.
Commercialized reproduction control vaccines
| Target antigen | Target species | Brand name | Distributor | Characteristic(s) | Reference or source |
|---|---|---|---|---|---|
| LHRH | Female cattle | Vaxstrate | Websters Animal Health (withdrawn in 1996) | LHRH peptide conjugated to ovalbumin; oil emulsion adjuvant | 76 |
| LHRH | Male pigs | Improvac | CSL Ltd. (now Pfizer Animal Health) | Peptide-protein conjugate and water-miscible adjuvant; control of boar taint | 53 |
| LHRH | Female horses | Equity | CSL Ltd. (now Pfizer Animal Health) | Peptide-protein conjugate and proprietary adjuvant (immunostimulating complex); control of estrus and estrus-related behavior | 54 |
| LHRH | Male dogs | Canine gonadotropin-releasing factor immunotherapeutic | Pfizer Animal Health | Peptide-protein conjugate and water-miscible adjuvant; treatment of benign prostatic hyperplasia | USDA |
| LHRH | Deer, bison, horses | GonaCon | USDA (registration reported to be in progress) | Peptide conjugated to keyhole limpet hemocyanin in mycobacterium-oil adjuvant (AdjuVac); contraceptive vaccine to control wildlife | 112 |
| ZP (ZPC/ZP3) antigen | Several species | SpayVac | ImmunoVaccine Technologies, Canada (no longer available) | Crude ZPA preparation; supplied to research groups only | 27 |
| Androstenedione | Ewes | Fecundin | Coopers Animal Health (withdrawn) | Linked to human serum albumin; increased ovulation/twinning | |
| Androstenedione | Ewes | Androvax | Agvax Pty. Ltd. (now Intervet) | Increased ovulation/twinning | |
| Androstenedione | Ewes | Ovastim | Virbac | Increased ovulation/twinning |