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Antipilin antibody titers of mice in response to aerosol infection with live B. mallei. Five mice were infected via small-particle aerosol with 230 CFU of live B. mallei. Serum was drawn at the indicated times and tested by ELISA for IgG antibodies against purified pilin. Columns show the geometric mean reciprocal antibody titers, and error bars show the standard errors of the geometric means. There was a significant increase in titer over time (P = 0.02).
