FIG. 4.

BMDC maturation and activation following stimulation with R. conorii or LPS. BMDCs of B6 and C3H mice were left untreated (gray solid peaks) or stimulated with R. conorii strain Malish (black heavy lines) or LPS (blue dotted lines). After 24 h of stimulation, cells were stained with monoclonal Ab specific for CD11c and CD86, CD80, CD40, MHC-II, or MHC-I. Histograms depict expression profiles of gated CD11c⁺ cells. Positive staining was determined based on staining profiles of isotype controls. Mean fluorescence intensities for each histogram are indicated in the table. Data are representative of three independent experiments with similar results.