Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Immunoglobulin responses to the HC50 domain of BoNT/A when it was administered as a mixed-mode vaccine. The polypeptide was given to mice (n = 10) in an initial i.m. injection with alum as an adjuvant and in two subsequent i.n. boosters with vitamin E as an adjuvant. The results demonstrated that the mixed-mode vaccination paradigm elicited substantial IgG (⧫) and IgA (•) responses.
