TABLE 2.

UPEC outer membrane subproteome following culture in urine

Identification	ORF	Function	Mra	pIa
IutA	c3623	Ferric aerobactin receptor	84,050	5.24
ChuA	c4308	Heme/hemoglobin receptor	71,100	5.02
NAb	c2482	Putative receptor for iron compound	79,178	5.42
IroB	c1254	Glucosyltransferase	42,306	6.06
FhuA	c0185	Ferrochrome-iron receptor	82,182	5.33
Iha	c3610	Iron-regulated adhesin, catecholate receptor	76,511	5.64
IroN	c1250	Siderophore receptor	79,385	5.79
IreA	c5174	Iron-regulated virulence protein	75,306	6.15
MetQ	c0238	d-Methionine binding lipoprotein	29,318	5.13
OmpF	c1071	Porin	39,354	4.78
TolC	c3781	Outer membrane efflux protein	55,053	5.80
OmpA	c1093	Porin	41,054	6.24
OmpC	c2758	Porin	41,225	4.59
Slp	c4304	Starvation-inducible outer membrane lipoprotein	22,210	6.27
YbhC	c0849	Pectin methylesterase lipoprotein	67,075	7.00
HemX	c4722	Putative uroporphyrin methyltransferase	43,957	4.61
BtuB	c4929	Vitamin B12 (cobalamin) receptor	68,397	5.42
SmpA	c3139	Small protein A (outer membrane lipoprotein)	12,302	8.71
OmpW	c1722	Pole-localized outer membrane protein	25,877	5.93
Tsx	c0521	Nucleoside-specific pore-forming protein	35,480	5.82
FadL	c2889	Outer membrane long-chain fatty acid transport protein	48,680	4.80
Ag43	c1273	Type V secretion/autotransporter, adhesin	113,152	6.20
AcrA	c0581	Acriflavine resistance and efflux protein	43,521	8.41
ZipA	c2946	Membrane-tethered cell division protein	36,967	5.63
YfgM	c3035	Membrane protein assembly complex	22,146	5.07
YfiO	c3117	Essential outer membrane lipoprotein	27,829	6.16
OmpX	c0900	Acid- or base-induced putative adhesin	18,603	6.56
DcrB	c4265	Outer membrane phage adsorption protein	22,160	6.11
FliC	c2338	Flagellin	60,938	4.68

^aTheoretical masses and isoelectric points were determined by using the ExPASy proteomics server UniProt Knowledgebase (http://ca.expasy.org).

^bNA, no gene name available.