TABLE 2.

HLA-DR binding of overlapping HspX peptides^a

Amino acids	Sequence	IC50 (μM)
		HLA−:DR*0101	DR*1501	DR*0301
1-20	MATTLPVQRHPRSLFPEFSE	15	22	>100
11-30	PRSLFPEFSELFAAFPSFAG	<0.7	<0.7	42
21-40	LFAAFPSFAGLRPTFDTRLM	5	0.9	68
31-50	LRPTFDTRLMRLEDEMKEGR	24	35	0.5
41-60	RLEDEMKEGRYEVRAELPGV	8	13	41
51-70	YEVRAELPGVDPDKDVDIMV	12	17	35
61-80	DPDKDVDIMVRDGQLTIKAE	5	3	4
71-90	RDGQLTIKAERTEQKDFDGR	14	9	>100
81-100	RTEQKDFDGRSEFAYGSFVR	6	1	>100
91-110	SEFAYGSFVRTVSLPVGADE	<0.7	<0.7	45
101-120	TVSLPVGADEDDIKATYDKG	>100	>100	>100
111-130	DDIKATYDKGILTVSVAVSE	>100	70	>100
121-140	ILTVSVAVSEGKPTEKHIQI	>100	>100	>100
125-144	SVAVSEGKPTEKHIQIRSTN	>100	>100	>100

^aT-cell epitopes and associated values are depicted in boldface.