FIG. 2.

P. falciparum isolates from Senegal exhibit minimal variation in the expression of PfRh1, PfRh2a, and PfRh2b. Western blots of supernatant extracts probed with antisera specific for PfRh2a, PfRh2b, PfRh1, or PfSera5 as a loading control. The various sizes of PfRh2a and PfRh2b in the different isolates result from both sequence polymorphisms in the repetitive regions of these proteins and proteolytic breakdown products that are commonly observed even in laboratory isolates. Additionally, some isolates contain a large sequence deletion in PfRh2b (indicated by an arrow).