TABLE 1.
Day of infection | Mouse group | Arthritis prevalence (no. of inflamed joints/ total no. of joints)a | Mean arthritis severity score ± SDb |
---|---|---|---|
10 | Isotype control | 3/10 | 0.4 ± 0.7 |
MZB cell depleted | 11/11c | 1.6 ± 0.7d | |
14 | Isotype control | 12/28 | 0.5 ± 0.7 |
MZB cell depleted | 17/23e | 1.1 ± 0.9f |
Arthritis prevalence was reported as the number of joints with inflammation over the total number of joints examined in each group.
Arthritis was scored on a scale of 0 (negative) to 3 (severe) and is reported as the average score of the inflamed joints in each mouse group. Three to seven mice were examined in each group. The data for the arthritis at 14 days is combined from two separate experiments.
MZB cell-depleted mice versus control mice, P = 0.001, Fisher's exact test.
P = 0.001, two-tailed Student's t test.
P = 0.046, Fisher's exact test.
P = 0.016, two-tailed Student's t test.