TABLE 3.
Sequence variations observed between the GenBank reference strains, the local reference strains, the WHO reference strains, and the 53 clinical specimens testedd
| Species | Nucleotide at position:
|
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 104 | 209 | 221 | 248 | 389 | 393 | 434 | 584 | 651 | 779 | 843 | 932 | 938 | |
| L. infantum MHOM/TN/80/IPT1a | T | T | A | C | A | C | A | G | A | C | T | G | T |
| L. infantum MCAN/GR/94/CRE69b | T | T | A | C | A | C | T | A | C | C | T | G | T |
| L. infantum MHOM/TN/80/IPT1c | T | T | A | C | A | C | T | A | C | C | T | G | T |
| L. donovani 2525M-C2-2Ma | C | T | A | C | A | C | A | G | A | C | T | A | C |
| L. donovani MHOM/IN/80/DD8b | T | C | T | T | G | T | T | A | C | C | C | G | C |
| L. donovani MHOM/IN/80/DD8c | T | C | T | T | G | T | T | A | C | C | C | G | C |
| L. chagasi MHOM/BR/74/PP75a | T | C | T | T | G | T | T | A | C | C | C | G | C |
| L. chagasi MHOM/TN/80/IPT1c | T | T | A | C | A | C | T | A | C | C | T | G | T |
| 13 clinical specimens | T | T | A | C | A | C | T | A | C | C | T | G | T |
| 2 clinical specimens | T | T | A | C | A | C | T | A | C | T | T | G | T |
| Position | 490 | 624 | |||||||||||
| L. major MHOM/SU/73/5-ASKHa | C | T | |||||||||||
| L. major MHOM/SU/73/5-ASKHb | C | T | |||||||||||
| L. major MHOM/SU/73/5-ASKHc | C | T | |||||||||||
| 25 clinical specimens | T | C | |||||||||||
| Position | 111 | 121 | 139 | 150 | 483 | 490 | 493 | 585 | 667 | 837 | 880 | ||
| L. aethiopica MHOM/ET/72/L100a | T | T | A | C | T | T | T | T | G | T | T | ||
| L. aethiopica MHOM/ET/72/L100c | T | T | A | C | C | C | T | T | G | T | T | ||
| L. aethiopica MHOM/ET/72/L100b | C | C | G | T | C | C | C | A | T | C | C | ||
| Position | 195 | 262 | 807 | ||||||||||
| L. braziliensis MHOM/BR/75/M2904a | T | A | T | ||||||||||
| L. braziliensis MHOM/EC/88/INH-03a | G | T | T | ||||||||||
| L. braziliensis MHOM/BR/84/LTB300b | A | T | C | ||||||||||
| L. braziliensis MHOM/BR/84/LTB300c | T | T | T | ||||||||||
| 5 clinical specimens | G | T | T | ||||||||||
| Position | 355 | ||||||||||||
| L. panamensis MHOM/BR/71/LS94a | G | ||||||||||||
| L. panamensis MHOM/PA/71/LS94c | G | ||||||||||||
| 1 clinical specimen | T | ||||||||||||
a
GenBank reference strain.
b
Local reference strain.
c
WHO reference strain.
d
Nucleotide location refers to the L. infantum MHOM/TN/80/IPT1 sequence (GenBank accession number AB095958).