TABLE 3.
Association among macrolide resistance genes and the emm types isolated during the 11 years of studya
| emm type | No. of invasive GAS isolates (no. of isolates with the indicated associated gene)
|
||
|---|---|---|---|
| 1994 to 1996 surveillance study | 1997 to 2002 | 2003 to 2005 surveillance study | |
| 1 | 16 | 8 | 17 [2 mef(A)] |
| 2 | 1 [1 mef(A)] | 1 [mef(A)] | 3 [2 mef(A)] |
| 3 | 6 | 7 | 9 |
| 4 | 3 [2 mef(A)] | 8 [4 mef(A)] | |
| 5 | 2 | 3 | |
| 6 | 5 [1 erm(B)] | 1 | 5 |
| 9 | 3 | ||
| 11 | 1 | 1 | 2 |
| 12 | 4 [1 erm(B)] | 11 [2 erm(B) 3 mef(A)] | |
| 18 | 1 | 2 | 7 [1 erm(B)] |
| 22 | 1 | 2 [2 erm(B)] | 1 |
| 24 | 1 | 1 | |
| 27/77 | 1 | 1 [1 erm(A)] | 2 [1 erm(A)] |
| 28 | 1 | 1 | 1 |
| 33 | 1 | ||
| 44/61 | 2 | 4 [1 mef(A)] | |
| 53 | 2 | ||
| 58 | 1 | 1 | |
| 68 | 1 | ||
| 70 | 1 | ||
| 75 | 4 | 1 | |
| 76 | 1 | ||
| 78 | 1 | 2 | |
| 79 | 1 | ||
| 85 | 1 | ||
| 87 | 1 | ||
| 89 | 19 [16 erm(B)] | 9 [9 erm(B)] | 2 [1 erm(B)] |
| 102 | 1 | ||
| 108 | 1 | 3 | 1 |
| 110 | 2 | ||
| 114 | 1 | ||
| 118 | 1 | 2 | |
| Total (n = 207) | 79 | 39 | 89 |
New associations observed in the Strep-EURO study are indicated in boldface.