TABLE 2.
Source | No. of mice tested/no. of Helicobacter spp. culture positive | WT/GEM: genotype (background) | Age (mo) | Helicobacter species identified | No. of isolates identified by:
|
|
---|---|---|---|---|---|---|
PCR | Sequencing | |||||
Commercial company 1 (Switzerland) | 2/2 | GEM (B6/G9) | 12+ | Helicobacter sp. strain MIT 96-1001 | 2 | |
Research institutions | ||||||
Institution 1 (Australia) | 2/0 | WT (C57BL/6) | 13+ | Negative | NA | NA |
Institution 2 (Canada) | 2/2 | GEM: Myr AKT | 9 | H. hepaticus | 2 | NA |
Institution 3 (Canada) | 2/2 | GEM: Lnk−/− (C57BL/6) | 17 | Mixed culture | NA | 1 |
Institution 4 (Canada) | 1/1 | WT (C57BL/6) | 8+ | H. hepaticus mixed culture | 1 | |
Institution 5 (England) | 2/2 | GEM: R6/1 (CBA/C57BL/6 F1) | 6+ | H. hepaticus | 2 | |
Institution 6 (France) | 1/0 | GEM: Apc Flox (C57BL/6) | 7+ | Negative | NA | NA |
Institution 7 (France) | 2/1 | GEM: PO cre (C57BL/6) | 10+ | Helicobacter sp. strain Hamster B (NCBI accession no. AF072333) | 1 | |
Institution 7 (France) | 2/0 | GEM: IGF-IR−/+ | 9+ | Negative | NA | NA |
Institution 8 (Germany) | 2/2 | GEM: D1 cre | 9+ | H. rodentium | 2 | |
Institution 9 (Japan) | 2/2 | GEM: Lefty1+/− (C57BL/6) | 5+ | Helicobacter sp. strain MIT 01-6451 | 1 | |
Institution 10 (Japan) | 2/2 | GEM: WGA | 7+ | Helicobacter sp. strain MIT 01-6451 | 2 | |
Institution 11 (The Netherlands) | 2/2 | GEM: GFAP-cre (FVB) | 8 | H. hepaticus | 2 | |
Institution 11 (The Netherlands) | 1/0 | GEM: p53-flox/Rb flox | 7+ | Negative | NA | NA |
Institution 12 (Netherlands) | 1/1 | GEM: rad23B+/− (C57BL/6) | 12+ | H. hepaticus and H. typhlonius | 2 | |
Institution 13 (The Netherlands) | 2/2 | GEM: cdx1−/− (C57BL/6) | 8+ | H. typhlonius | 2 | |
Institution 14 (Scotland) | 3/3 | GEM: Alpha V Flox | 9 | H. hepaticus | 3 | |
Institution 14 (Scotland) | 2/2 | GEM: Intavflox-cre | 20+ | H. mastomyrinus | 2 | |
Institution 15 (Sweden) | 2/2 | GEM: Cre 151 | 6 | H. typhlonius | 1 | |
Total | 35/28 | 16 | 9 |
WT, wild type; GEM, genetically engineered mice; NA, not applicable.