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. 2007 May 16;45(7):2166–2172. doi: 10.1128/JCM.00137-07

TABLE 2.

Helicobacter species isolated from commercial and research mouse colonies in Europe, Asia, Australia, and Canadaa

Source No. of mice tested/no. of Helicobacter spp. culture positive WT/GEM: genotype (background) Age (mo) Helicobacter species identified No. of isolates identified by:
PCR Sequencing
Commercial company 1 (Switzerland) 2/2 GEM (B6/G9) 12+ Helicobacter sp. strain MIT 96-1001 2
Research institutions
    Institution 1 (Australia) 2/0 WT (C57BL/6) 13+ Negative NA NA
    Institution 2 (Canada) 2/2 GEM: Myr AKT 9 H. hepaticus 2 NA
    Institution 3 (Canada) 2/2 GEM: Lnk−/− (C57BL/6) 17 Mixed culture NA 1
    Institution 4 (Canada) 1/1 WT (C57BL/6) 8+ H. hepaticus mixed culture 1
    Institution 5 (England) 2/2 GEM: R6/1 (CBA/C57BL/6 F1) 6+ H. hepaticus 2
    Institution 6 (France) 1/0 GEM: Apc Flox (C57BL/6) 7+ Negative NA NA
    Institution 7 (France) 2/1 GEM: PO cre (C57BL/6) 10+ Helicobacter sp. strain Hamster B (NCBI accession no. AF072333) 1
    Institution 7 (France) 2/0 GEM: IGF-IR−/+ 9+ Negative NA NA
    Institution 8 (Germany) 2/2 GEM: D1 cre 9+ H. rodentium 2
    Institution 9 (Japan) 2/2 GEM: Lefty1+/− (C57BL/6) 5+ Helicobacter sp. strain MIT 01-6451 1
    Institution 10 (Japan) 2/2 GEM: WGA 7+ Helicobacter sp. strain MIT 01-6451 2
    Institution 11 (The Netherlands) 2/2 GEM: GFAP-cre (FVB) 8 H. hepaticus 2
    Institution 11 (The Netherlands) 1/0 GEM: p53-flox/Rb flox 7+ Negative NA NA
    Institution 12 (Netherlands) 1/1 GEM: rad23B+/− (C57BL/6) 12+ H. hepaticus and H. typhlonius 2
    Institution 13 (The Netherlands) 2/2 GEM: cdx1−/− (C57BL/6) 8+ H. typhlonius 2
    Institution 14 (Scotland) 3/3 GEM: Alpha V Flox 9 H. hepaticus 3
    Institution 14 (Scotland) 2/2 GEM: Intavflox-cre 20+ H. mastomyrinus 2
    Institution 15 (Sweden) 2/2 GEM: Cre 151 6 H. typhlonius 1
    Total 35/28 16 9
a

WT, wild type; GEM, genetically engineered mice; NA, not applicable.