TABLE 1.

Agreement between CLSI reference method M38-A and the Sensititre YeastOne method for testing the susceptibility of filamentous molds

Test organism(s)	No. of strains	MICa by CLSI/MIC by YO		% Agreement within the following log2 dilution
		MIC90	Range	±2	±1	0
All isolates	249			97	94	56
Aspergillus	179			97	94	50
A. fumigatus	96	1/1	0.015->8/0.015->8	96	94	54
A. flavus	32	0.5/0.25	0.12-1/0.06-0.25	100	91	34
A. niger	20	0.25/0.25	0.03-0.25/0.03-0.25	100	100	70
A. terreus	19	0.25/0.25	0.015-0.5/0.03-0.5	100	95	32
A. nidulans	3	—b	0.015-0.06/0.015-0.06	100	100	33
A. oryzae	3	—	0.12-0.5/0.12-0.25	100	100	33
A. ustus	3	—	2->8/>8	67	67	67
A. versicolor	3	—	0.06->8/0.03->8	100	100	67
Fusarium	41			100	98	90
F. solani	14	>8/>8	>8/>8	100	100	100
Fusarium spp.	8	—	0.5->8/0.5->8	100	100	88
F. oxysporum	7	—	2->8/2->8	100	100	100
F. moniliforme	6	—	1-2/1-2	100	100	67
F. proliferatum	6	—	4->8/1->8	100	83	83
Zygomycetes	29			93	86	45
Absidia
Absidia spp.	2	—	1-2/0.5	100	50	0
A. corymbifera	1	—	2/1	100	100	0
Mucor
M. circinelloides	1	—	2/0.5	100	0	0
M. ramosissimus	1	—	2/1	100	100	0
Mucor spp.	1	—	2/2	100	100	100
Rhizopusc				96	96	57
Rhizopus spp.	17	1/1	0.06->8/0.12->8	100	100	47
R. arrhizus	4	—	0.03-2/0.25->8	50	50	50
R. microsporus	2	—	0.5/0.5	100	100	100

^aIn micrograms per milliliter. YO, Sensititre YeastOne.

^b—, not determined. MIC₉₀s were calculated only when >10 isolates were tested.

^cCLSI MICs were read after 24 h.