TABLE 3.
Crude OR and 95% CI for mortality according to biofilm production by isolates of Candida species
| Candida species | Patients infected by biofilm-positive isolate
|
Patients infected by biofilm-negative isolate
|
OR (95% CI) | Pa | ||
|---|---|---|---|---|---|---|
| Total no. | No. (%) who died | Total no. | No. (%) who died | |||
| C. albicans | 38 | 32 (84.2) | 130 | 65 (50) | 3.90 (1.72-8.83) | <0.001 |
| C. parapsilosis | 14 | 10 (71.4) | 50 | 14 (28) | 4.16 (1.46-11.82) | 0.003 |
| C. tropicalis | 20 | 8 (40) | 8 | 4 (50) | 0.88 (0.54-1.45) | 0.62 |
| C. glabrata | 6 | 4 (66.6) | 20 | 11 (55) | 1.46 (0.32-6.62) | 0.61 |
| Otherb | 2 | 2 (100) | 6 | 4 (66.6) | 0.34 | |
| Total | 80 | 56 (70) | 214 | 98 (45.7) | 2.76 (1.55-5.00) | <0.001 |
a
P value comparing the number of patients who were infected with a biofilm-positive isolate and died to the number of patients infected with a biofilm-negative isolate and died.
b
Includes Candida guilliermondii (three patients), Candida krusei (two patients), and Candida spp. (three patients).