TABLE 2.

Reproducibility of inhibition zone diameters, in millimeters, obtained by the disk diffusion method with five antifungal agents for 72 mold isolates at two of the five centers^a

Antifungal agent and mediumb	% within 2-SD zone at:
	24 h	48 h	72 h
Itra
MH	96	91	88
MGM	87	82	82
Posa
MH	97	95	92
MGM	96	96	94
Vori-1
MH	97	94	93
MGM	97	95	90
Vori-10
MH	92	93	92
MGM	92	93	92
Cas-BBL
MH	100	96	95
MGM	96	94	87
Cas-Oxoid
MH	100	97	97
MGM	100	100	97
Amb
MH	95	95	95
MGM	100	95	91

^aPercentages of replicate zone diameters within 2 standard deviations of the mean; each of the 72 isolates was tested on 3 different days in two of the five laboratories with each antifungal agent. Inhibition zone diameters, in millimeters, on both MH and MGM agar were read at 16 to 24, 48, and 72 h.

^bItra, itraconazole 10-μg disk; Posa, posaconazole 5-μg disk; Cas-BBL and Cas-Oxoid, caspofungin 5-μg disks from two sources; Vori-1 and Vori-10, voriconazole 1-μg and 10-μg disks, respectively; Amb, amphotericin B 10-μg disk.