TABLE 3.
Inhibition zone diameters obtained on MH agar by the disk diffusion method for two QC isolatesa
| QC isolateb and antifungal agent | Zone range in millimeters (% agreement) at:
|
||
|---|---|---|---|
| 24 h | 48 h | 72 h | |
| Paecilomyces variotii ATCC 3630 | |||
| Itra | 25-31 (99) | 23-31 (94) | 24-31 (97) |
| Posa | 35-46 (100) | 37-45 (97) | 37-44 (97) |
| Vori-1 | 40-53 (94) | 41-53 (94) | 41-53 (100) |
| Vori-10 | 56-64 (97) | 60-71 (86) | 61-73 (89) |
| Cas-BBL | 23-29 (100) | 23-30 (97) | 24-30 (97) |
| Cas-Oxoid | 23-34 (100) | 23-34 (97) | 22-33 (89) |
| Amb | 13-22 (94) | 9-19 (83) | 10-19 (89) |
| Candida krusei ATCC 6258 | |||
| Itra | 21-30 (100) | 20-29 (100) | 20-28 (100) |
| Posa | 31-43 (97) | 30-41 (97) | 30-41 (97) |
| Vori-1 | 29-38 (100) | 25-35 (100) | 24-36 (97) |
| Vori-10 | 47-59 (92) | 46-60 (97) | 53-61 (92) |
| Cas-BBL | 14-24 (100) | 18-27 (97) | 17-25 (97) |
| Cas-Oxoid | 21-29 (100) | 21-30 (100) | 21-32 (100) |
| Amb | 19-27 (100) | 15-25 (97) | 13-25 (97) |
a
Tests were performed 5 to 16 times for each isolate in each of the five laboratories for each disk and incubation time on MH agar.
b
Itra, itraconazole 10-μg disk; Posa, posaconazole 5-μg disk; Cas-BBL and Cas-Oxoid, caspofungin 5-μg disks from two sources; Vori-1 and Vori-10, voriconazole 1-μg and 10-μg disks, respectively; Amb, amphotericin B 10-μg disk.