FIG. 1.
Generation of standard curves for M. paratuberculosis using the MGIT 960 culture system. (A) Universal standard curve for the pooled data from 12 strains of M. paratuberculosis [log10 CFU inoculum size = 9.515 × e(−0.03977 × TTD) − 2.143]. (B) Representative strain-specific standard curve of M. paratuberculosis ATCC 19698 [log10 CFU inoculum size = 8.802 × e(−0.0538 × TTD) − 0.93851]. The blue line shows the best-fitting curve for all strains. The red dotted lines and green dotted lines show 95% PIs and 95% CIs, respectively.