Skip to main content
. 2007 Apr 25;45(6):1912–1919. doi: 10.1128/JCM.01251-06

FIG. 1.

FIG. 1.

Microscopic studies of hMPV-infected (a to f) and uninfected (g) Vero E6 cell lines. The various CPEs were induced by the hMPV strains. (a and b) Vero E6 cell primary culture 17 days after inoculation with 1159-Yamagata-05 and 1645-Yamagata-05, respectively. Early CPEs for hMPV were recognized as granular and roundup cell formation, and there was no clear syncytium formation. (c and d) Vero E6 cell primary culture 29 days after inoculation with 970-Yamagata-05 and 1159-Yamagata-05, respectively. The granular formation has spread and progressed, though the Vero E6 monolayer is still stable. (e) Vero E6 cell culture 4 days after inoculation with viral fluid from 1159-Yamagata-05 after two passages. Infected cells showed marked syncytium formation progressing to detachment from the cell monolayer. (f) Vero E6 cell culture 4 days after inoculation with viral fluid from 871-Yamagata-05 after two passages. The CPE consisted of roundup cells and small rather than large syncytia. (g) Uninfected Vero E6 cells 22 days after preparation. Original magnifications, ×100 (a and c) and ×200 (b and d to g).