TABLE 1.
System and phenotype | No. of strains with the indicated phenotype as determined by the BACTEC 460TB method
|
|||||||
---|---|---|---|---|---|---|---|---|
INH
|
RIF
|
EMB
|
STR
|
|||||
R | S | R | S | R | S | R | S | |
MB/BacT | ||||||||
R | 47 | 2 | 14 | 1 | 9 | 0 | 12 | 0 |
S | 1 | 32 | 0 | 67 | 3 | 70 | 6 | 64 |
BACTEC MGIT 960 | ||||||||
R | 45 | 0 | 14 | 1 | 11 | 0 | 17 | 3 |
S | 3 | 34 | 0 | 67 | 1 | 70 | 1 | 61 |
Drug concentrations used for MB/BacT and MGIT 960 testing were 0.1 μg/ml for isoniazid, 1 μg/ml for rifampin, 5 μg/ml for ethambutol, and 1 μg/ml for streptomycin. Drug concentrations used for BACTEC 460TB testing were 0.1 μg/ml for isoniazid, 2 μg/ml for rifampin, 7.5 μg/ml for ethambutol, and 6 μg/ml for streptomycin. INH, isoniazid; RIF, rifampin; EMB, ethambutol; STR, streptomycin; S, susceptible; R, resistant.