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. 2007 May 7;35(Web Server issue):W568–W572. doi: 10.1093/nar/gkm289

Figure 1.

Figure 1.

Flowchart of Frog processing. The compound (a) is decomposed as a graph involving rings and acyclic elements (b). Acyclic elements are built from scratch. Ring conformations are extracted from a library of rings. Then all the elements are assembled to produce the complete compound structure (c).