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(A) The partial result of iPDA on protein P53_HUMAN (P04637). (B) The partial conservation plot of ClustalW and WildSpan, after invoking the second run of pattern mining on the first predicted disordered region. (C) The discovered conserved segment ‘FxxLW’ contains three important residues for MDM2 binding, where chain B is a short polypeptide of p53 and chain A is the protein MDM2 (PDB structure used: 1YCQ).
