Table 3.
Comparison with other existing packages
| Method | Sens. | Spec. | Accu. | MCC | Prob. Excess |
|---|---|---|---|---|---|
| DisPSSMP2 | 0.848 | 0.867 | 0.862 | 0.681 | 0.715 |
| VSL2 (33) | 0.821 | 0.815 | 0.817 | 0.594 | 0.636 |
| DisPSSMP (8) | 0.814 | 0.818 | 0.817 | 0.592 | 0.632 |
| IUPred[long] (34,35) | 0.629 | 0.954 | 0.863 | 0.644 | 0.583 |
| RONN (18) | 0.661 | 0.882 | 0.820 | 0.549 | 0.542 |
| FoldIndex (36,37) | 0.675 | 0.812 | 0.774 | 0.467 | 0.487 |
| IUPred[short] (34,35) | 0.549 | 0.934 | 0.826 | 0.541 | 0.483 |
| SPRITZ[long] (38) | 0.543 | 0.917 | 0.812 | 0.506 | 0.460 |
| DISOPRED2 (39) | 0.455 | 0.976 | 0.834 | 0.550 | 0.430 |
| PONDR (15) | 0.617 | 0.804 | 0.751 | 0.407 | 0.420 |
| DISpro (40) | 0.390 | 0.989 | 0.821 | 0.530 | 0.379 |
| FoldUnfold (41) | 0.631 | 0.737 | 0.707 | 0.343 | 0.368 |
| DisEMBL[465] (7) | 0.345 | 0.980 | 0.802 | 0.465 | 0.326 |
| DisEMBL[hot] (7) | 0.500 | 0.807 | 0.721 | 0.308 | 0.308 |
| PreLink (42) | 0.302 | 0.963 | 0.777 | 0.378 | 0.265 |
| SPRITZ [short] (38) | 0.290 | 0.893 | 0.724 | 0.226 | 0.183 |
| DisEMBL[coils] (7) | 0.723 | 0.432 | 0.514 | 0.143 | 0.155 |
| GlobPlot (43) | 0.321 | 0.814 | 0.676 | 0.146 | 0.136 |