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Mortality (A), clinical score (B), and body weight (C) of Swiss Webster mice infected i.c. with SPBNGAN-GAN, SPBNGAK-GAK, SPBNGAK-GAN, or SPBNGAN-GAK. Data are mean (± standard error) values obtained with 10 mice that were infected i.c. with 103 FFU. Asterisks in panels B and C indicate significant differences in the decrease of body weight (***, P ≤ 0.001; **, P ≤ 0.01; *, P ≤ 0.05) between SPBNGAK-GAK-infected and SPBNGAK-GAN- or SPBNGAN-GAK-infected mice.
