TABLE 3.

Diverse mutations in the HSV-1 tk seven-G homopolymer region detected in individual ganglia from patient 708

Source of DNA	No. of clones sampled	No. of clonesa with:					% of mutant clones
		7-G (WT) sequence	1-G del	1-G ins	2-G ins	3-G ins
LTG	48	46	2	0	0	0	4.2
LT2 ganglion	23	16	0	0	6	1	30
LT6 ganglion	75	59	0	2	12	2	21
LT7 ganglion	23	20	1	2	0	0	13
LT8 ganglion	23	12	0	2	6	3	48
LT9 ganglion	23	10	0	1	10	2	57
LL1 ganglion	23	15	0	7	0	1	35
LL3 ganglion	21	5	0	1	12	3	76
LS1 ganglion	24	19	0	0	5	0	21
LS2 ganglion	24	18	1	2	2	1	25
RT6 ganglion	23	21	2	0	0	0	8.7
RS1 ganglion	24	24	0	0	0	0	0.0
Total	354	265	6	17	53	13	25

^adel, deletion; ins, insertion.