FIG. 8.

Schematic diagram of structure of Zta and requirement of the CT region for function. (A) The schematic diagram of the structure of Zta is based on the crystal structure of Zta, which ends at D236 (23). The additional information that the distal part of the CT region (ending at F245) contacts the zipper and locations of the termination mutants I231ter and M221 ter are shown. (B) Locations of amino acids that contribute to dimerization are shown in bold and underlined. Each line represents mutants that support the conclusion shown on the right-hand side. Transactivation in vivo is represented as TA.