FIG. 1.
Schematic representation of the sequences of the C-terminal domains of N and P proteins used or discussed in this article. (From top to bottom) SeV NTAIL, with the striped region indicating the SeV P protein binding site on NTAIL, as suggested by the work of Çevik et al. (7), and the black regions indicating the two predicted α helices (Jpred program). Two shorter SeV NTAIL constructs were also used: NTAIL(443-524) and NTAIL(443-501). For comparison, the MV NTAIL is shown with the two regions involved in binding to the C-terminal domain of MV P protein (XD) indicated: region 488 to 504, which undergoes induced α-helical folding (16, 22), and the additional site region 517 to 525 found by Bourhis et al. (5). The C-terminal domain of SeV P protein (PX [474 to 568]) and the C-terminal domain of MV protein P (XD [459 to 507]) are also depicted. In the last two domains, the gray regions correspond to the three α helices observed in these domains.