FIG. 3.
mMDDC viral capture increases over time, and captured virus has a longer life span than in iMDDCs. (A to D) Time course of HIVNL43/eGFP or HIVNFN-SX capture by mMDDCs and iMDDCs showed that mMDDC viral capture increases over time while remaining constant in iMDDCs. (E and F) Fate of HIVNFN-SX captured for 2 h by mMDDCs and iMDDCs, respectively, monitored during 2 days. Cell-associated p24gag measured by ELISA is shown as closed symbols, while p24gag released to the cell culture medium is shown as open symbols. Captured virus showed a prolonged life span in mMDDCs. Data (means and SEM from two independent experiments) include cells from six different donors.