FIG. 1.
Electron micrographs showing the entry of RDV into insect vector cells. (a) Attachment of RDV particles to the plasma membranes of VCMs 30 min p.i. (b and c) Uptake of RDV particles in coated pits (arrows) 1 h p.i. (c and d) RDV particles internalized within coated pits (arrowheads) 1 h p.i. (e) Single RDV particle enclosed in vesicles (arrows) 2 h p.i. (f) Vesicles with an RDV particle(s) are in close proximity to other vesicles (arrows), possibly prior to fusion, 4 h p.i. (g) RDV particles in electron-lucent compartment (arrow) 4 h p.i. (h) Immunodetection of RDV particles in multivirus-containing compartments using gold particles conjugated to P2-specific IgG 4 h p.i. Bars, 200 nm.