TABLE 1.
Study design
| Group | Hamster ID no.a | Fateb | Day | Necropsy |
|---|---|---|---|---|
| ANDV time course | 201 | FD | 13 | |
| 202 | FD* | 7 | ||
| 203 | FD | 11 | ||
| 204 | FD | 11 | ||
| 205 | SAC | 14 | Yes | |
| 206 | EUTH | 12 | Yes | |
| 207 | SAC | 14 | Yes | |
| 208 | FD | 11 | ||
| SNV time course | 209 | |||
| 210 | Survived | |||
| 211 | Survived | |||
| 212 | Survived | |||
| 213 | Survived | |||
| 214 | Survived | |||
| 215 | Survived | |||
| 216 | Survived | |||
| ANDV serial pathology | 217 | SAC | 2 | Yes |
| 218 | SAC | 2 | Yes | |
| 219 | SAC | 2 | Yes | |
| 220 | SAC | 4 | Yes | |
| 221 | SAC | 4 | Yes | |
| 222 | SAC | 4 | Yes | |
| 223 | SAC | 6 | Yes | |
| 224 | SAC | 6 | Yes | |
| 225 | SAC | 6 | Yes | |
| 226 | SAC | 8 | Yes | |
| 227 | SAC | 8 | Yes | |
| 228 | SAC | 8 | Yes | |
| 229 | SAC | 10 | Yes | |
| 230 | SAC | 10 | Yes | |
| 231 | SAC | 10 | Yes | |
| 232 | FD | 10 | ||
| 233 | SAC | 12 | Yes | |
| 234 | FD | 14 | ||
| 235 | FD | 10 | ||
| 236 | FD | 11 | ||
| 237 | EUTH | 10 | ||
| 238 | EUTH | 12 | Yes | |
| 239 | SAC | 14 | Yes | |
| 240 | EUTH | 10 | ||
| SNV serial pathology | 241 | SAC | 2 | Yes |
| 242 | SAC | 2 | Yes | |
| 243 | SAC | 2 | Yes | |
| 244 | SAC | 4 | Yes | |
| 245 | FD* | −7 | Yes | |
| 246 | SAC | 4 | Yes | |
| 247 | SAC | 6 | Yes | |
| 248 | SAC | 6 | Yes | |
| 249 | SAC | 6 | Yes | |
| 250 | SAC | 8 | Yes | |
| 251 | SAC | 8 | Yes | |
| 252 | SAC | 8 | Yes | |
| 253 | SAC | 10 | Yes | |
| 254 | SAC | 10 | Yes | |
| 255 | SAC | 10 | Yes | |
| 256 | SAC | 12 | Yes | |
| 257 | SAC | 12 | Yes | |
| 258 | SAC | 12 | Yes | |
| 259 | SAC | 14 | Yes | |
| 260 | SAC | 14 | Yes | |
| 261 | SAC | 14 | Yes | |
| 262 | SAC | 16 | Yes | |
| 263 | SAC | 16 | Yes | |
| 264 | SAC | 16 | Yes | |
| No challenge | 265 | SAC | −7 | Yes |
| 266 | SAC | −7 | Yes | |
| 267 | SAC | −7 | Yes |
a
ID, identification.
b
FD, found dead; FD*, suspect death due to blood draw; SAC, no signs of disease when sacrificed; EUTH, moribund animal euthanized.