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Detection of 3'-UTR mutations in blood samples of patients with CHD. (A) sequence electropherograms for c.+119A>T, showing heterozygous (AT) and homozygous (AA) genotypes; (B) in a family of four in which the two children had ASD; the father and the children had the heterozygous genotype AT (+), the mother was homozygous for the reference allele AA; (C) Compared to the reference sequence and on the basis of Vienna RNA folding procedure, c.+119A>T is predicted to affect RNA folding.
