Table 1.
Human PKD can replace Drosophila PKD activity
| UAS-Line | n | 0/1 | 2 | 3 |
| GFP-lacZ | 19 | 0% | 0% | 100% |
| PKD-WT10-2 | 44 | 77,2% | 4,6% | 18,2% |
| PKD-SE139-2 | 35 | 94,3% | 2,9% | 2,8% |
| hPKD2II-3 | 22 | 63,6% | 36,4% | 0% |
| hPKD2X-2 | 16 | 89,0% | 8,3% | 2,7% |
| hPKD3V-1 | 28 | 79,6% | 14,3% | 6,1% |
| hPKD3X-1 | 21 | 86,5% | 8,1% | 5,4% |
| PKCi | 23 | 0% | 0% | 100% |
The given UAS-line was overexpressed along the antero-posterior border with help of the ptc-Gal4 driver line together with UAS-dsPKD6-4. As control, ptc > dsPKD6-4 was crossed to UAS-GFP-lacZ and wings used for comparison. Wings of at least ten flies were mounted and examined at high magnification. n, number of wings scored. 0/1, wild type looking wing; 2, weak phenotype; 3, phenotype indistinguishable from control. Numbers represent percentage of wings with given phenotype.