Table 2.
Subunit | Nucleotide Position | Dahl S and R | Wistar | Brown Norway |
ENaC α | -705 | TT | TT | CC, CT, TT |
-1050 | AA | AA | GG, GA, AA | |
-1247 | TT | TT | AA, AT, TT | |
-1788 | Deletion of 5GCTs | Deletion of 5GCTs | ||
ENaC β | -34381 | AA | GG, GA, AA | GG, GA, AA |
-34648 | AA | GG, GA, AA | GG | |
ENaC γ | -1118 | Insertion of CCCCCA | ||
-1588 | CC | AA, AC, CC | AA | |
-2054 | TT | TT, CT, CC | CC, CT, TT | |
-2386 | GG | AA* | AA | |
-2525 | AA | GG, GA, AA | GG | |
-2561 | GG | AA, AG, GG | AA | |
-3313 | CC | CC | TT |
Numbering starts at the A nucleotide of the primary initiation codon [15].
* GG genotype was previously reported [7].