Figure 6.

tiar^−/− ES cell proliferation defect. tiar^−/− ES (solid lines) and control tiar^+/+ or tiar^+/− ES (dashed lines) cell lines were grown in media containing methylcellulose in the absence (A) or presence (B) of exogenous LIF. Cell growth was determined by using [³H]thymidine incorporation at the indicated times. Values represent mean values of triplicate samples with vertical bars indicating the SDs. Data are shown for two independent tiar^−/− ES cell lines and control tiar^+/+ and tiar^+/− cell lines. Similar results were obtained in four additional experiments.