Table 6.

Comparisons of the parameters of the IAHG scoring system among patients with AIH/overlap syndromes (n = 10), coincidence of AIH and other liver disease (n = 14) and AIH patients (n = 43).

Characteristics	Patients with AIH/overlap syndromes no. of patients (%)	Patients with coincidence of AIH and other liver disease no. of patients (%)	Patients with AIH no. of patients (%)	P value
Gender
Female	5 (50)	7 (50)	33 (76.7)	NS
Male	5 (50)	7 (50)	10 (23.3)
ALP/ALT ratio
Positive: score +2	8 (80)	12 (85.7)	41 (95.3)	NS
Negative: score 0, -2	2 (20)	2 (14.3)	2 (4.7)
Serum globulin or IgG above normal
Positive (score ≥ 1)	7 (70)	10 (71.4)	34 (79.1)	NS
Negative (score 0)	3 (30)	4 (28.6)	9 (20.9)
ANA, SMA or anti-LKM
Positive (titre ≥ 1:40)	9 (90)	14 (100)	43(100)	0.055*
Negative	1 (10)	0	0
AMA
Positive (titre ≥ 1:40)	4 (40)	0	0	<0.001*
Negative	6 (60)	14(100)	43 (100)
Hepatitis viral markers
Yes	0	8 (57.1)	0	<0.001*
No	10 (100)	6 (42.9)	43 (100)
History of illicit drug use
Yes	0	0	1 (2.3)	NS
No	10 (100)	14 (100)	42 (97.7)
Average alcohol intake
<25 g/day	10 (100)	11 (78.6)	42 (97.7)	0.022*
>60 g/day	0	3 (21.4)	1 (2.3)
Histological score
Positive (score > 0)	3 (30)	10 (71.4)	35 (81.4)	0.005*
Negative (score ≤ 0)	7 (70)	4 (28.6)	8 (18.6)
Aggregate histological score (mean ± SD)	-2.1 ± 4.4	2.14 ± 1.7	2.73 ± 1.98	0.001**
Other autoimmune disease
Yes	5 (50)	2 (14.3)	25 (58.1)	NS
No	5 (50)	12 (85.7)	18 (41.9)
Aggregate AIH score (mean ± SD)	9.3 ± 4.8	10.5 ± 3.7	17 ± 3.05	<0.001**

Abbreviations are same as in text; NS: not statistically significant; SD: standard deviation; * Total x square (comparison amongst the three groups of patients; for statistical significance between groups see text of results, subheading Comparison between groups, third paragraph); **Kruskal-Wallis test (comparison amongst the three groups of patients; for statistical significance between groups see text of results, subheading Comparison between groups, third paragraph).